Jen Burgess is attacked by her sinister sister Cassie, which results in Cassie being into psychiatric treatment while her twin daughters are sent to live with Jen. But do the twins have a hidden agenda their wealthy aunt isn't aware of?

In Seattle, the successful forensic psychiatrist and college professor Jack Gramm is in evidence since he was responsible for the condemnation of the serial killer Jon Forster, influencing the jury to sentence him to the death row. Jon accuses Jack of manipulation, inducing one witness and sister of one of his victims to testify against him. On the eve of Jon's execution, Jack receives a phone call telling him that he has only eighty-eight minutes of life, while a killer is copycatting Jon, killing women with the same "modus-operandi" and is investigated by Seattle Slayer Task Force. With the support of associate Shelly Barnes, an FBI agent, his friend Frank Parks, and his assistant Kim Cummings, Jack investigates some weird and problematic students, a security guard of the campus and the woman with whom he had one night stand.